SCHEMBL3714902

SCHEMBL3714902

CCP(=O)(OC)c1ccc2oc(C=C(F)c3ccccc3)nc2c1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UTRN P46939 20/20 0.68
HTR2B P41595 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3714900 0.82 UTRN (0.65) UTRNHTR2B
SCHEMBL3717358 0.77 KMT2A (0.53) UTRN
SCHEMBL3715823 0.73 GAA (0.38) UTRN
SCHEMBL15423678 0.68 UTRN (0.81) UTRNHTR2B
SCHEMBL29411312 0.67 UTRN (1.00) UTRNHTR2B
SCHEMBL3716191 0.65 KMT2A (0.49) UTRN
SCHEMBL28468331 0.63 GAA (0.57)
SCHEMBL777171 0.63 AOX1 (0.47) UTRN
SCHEMBL3717356 0.60 CYP1A2 (0.50) UTRN
SCHEMBL28429675 0.60 RAB9A (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010112092-A1 COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULARY DYSTROPHY BIOMARIN IGA, LTD. (BS) 2010-10-07 WO claimed
WO-2010112092-A1 COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULARY DYSTROPHY BIOMARIN IGA, LTD. (BS) 2010-10-07 WO disclosed