Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | BACE1 | P56817 | 6/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13191096 | 0.83 | HRH3 (0.42) | BACE1CARM1PRMT6MAP4K4 | |
| SCHEMBL3715263 | 0.81 | BCHE (0.55) | ACHEBACE1BCHEHTR2CHTR2B | |
| SCHEMBL29227123 | 0.80 | SMN1; SMN2 (0.53) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL30873432 | 0.80 | SMN1; SMN2 (0.53) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL22361722 | 0.79 | CARM1 (0.49) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL8081164 | 0.77 | ACHE (0.68) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL7213077 | 0.77 | ACHE (0.65) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL30873498 | 0.76 | ALDH1A1 (0.47) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL29227095 | 0.76 | ALDH1A1 (0.47) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL20847771 | 0.76 | NPC1 (0.65) | BCHEMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111353-A1 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | ACADIA PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |