Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721958 | 0.97 | CYP3A4 (0.53) | TSHRL3MBTL1CYP3A4TDP1MAPK1 | |
| SCHEMBL12731182 | 0.92 | L3MBTL1 (0.49) | TSHRL3MBTL1CYP3A4TDP1MAPK1 | |
| SCHEMBL19024842 | 0.89 | NPC1 (0.53) | TSHRCYP3A4MAPTNPC1PRSS1 | |
| SCHEMBL12567464 | 0.88 | CYP3A4 (0.47) | TSHRL3MBTL1CYP3A4TDP1MAPK1 | |
| SCHEMBL5961854 | 0.88 | L3MBTL1 (0.46) | TSHRL3MBTL1CYP3A4TDP1MAPK1 | |
| SCHEMBL12567508 | 0.85 | KMT2A (0.50) | L3MBTL1CYP3A4TDP1MAPK1ALDH1A1 | |
| SCHEMBL12567471 | 0.85 | CYP3A4 (0.47) | TSHRL3MBTL1CYP3A4TDP1MAPK1 | |
| SCHEMBL12567532 | 0.85 | THRB (0.45) | TSHRL3MBTL1CYP3A4TDP1MAPK1 | |
| SCHEMBL12567550 | 0.85 | HIF1A (0.43) | TSHRL3MBTL1CYP3A4TDP1MAPK1 | |
| SCHEMBL11330584 | 0.85 | L3MBTL1 (0.65) | TSHRL3MBTL1CYP3A4TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112831-A1 | LIQUID CRYSTAL ELASTOMER BEADS | UNIVERSITY OF YORK (GB) | 2010-10-07 | — | — | WO | disclosed |