Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 5/20 | 0.41 |
| ▸ | THRA | P10827 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781005 | 1.00 | TSHR (0.48) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL21463008 | 0.93 | TSHR (0.43) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL5053799 | 0.92 | TSHR (0.52) | TSHRHPGDZDHHC20ZDHHC2THRB | |
| SCHEMBL1408575 | 0.84 | — | — | |
| SCHEMBL2354518 | 0.79 | HCAR2 (0.45) | ZDHHC20ZDHHC2THRBHCAR2ATM | |
| SCHEMBL2355219 | 0.79 | HCAR2 (0.45) | ZDHHC20ZDHHC2THRBHCAR2ATM | |
| SCHEMBL2354511 | 0.79 | HCAR2 (0.45) | ZDHHC20ZDHHC2THRBHCAR2ATM | |
| SCHEMBL2354333 | 0.79 | HCAR2 (0.45) | ZDHHC20ZDHHC2THRBHCAR2ATM | |
| SCHEMBL2354341 | 0.79 | HCAR2 (0.45) | ZDHHC20ZDHHC2THRBHCAR2ATM | |
| SCHEMBL2353931 | 0.79 | CES2 (0.38) | TSHRALDH1A1MEN1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094558-A1 | ABRASION-RESISTANT TINTABLE COATING | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2010-08-26 | — | — | WO | disclosed |