SCHEMBL3715513

SCHEMBL3715513

Cc1cn([C@@]2(N)C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.51
POLA1 P09884 1/20 0.51
POLD1 P28340 1/20 0.51
TK1 P04183 3/20 0.45
DTYMK P23919 2/20 0.44
P2RY6 Q15077 5/20 0.43
P2RY2 P41231 5/20 0.43
P2RY4 P51582 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5191085 0.89 POLB (0.50) POLBPOLA1POLD1TK1DTYMK
SCHEMBL7240891 0.88 POLB (0.52) POLBPOLA1POLD1TK1DTYMK
SCHEMBL29538414 0.87 POLB (0.51) POLBPOLA1POLD1TK1DTYMK
SCHEMBL29723202 0.87 POLB (0.51) POLBPOLA1POLD1TK1DTYMK
SCHEMBL31742537 0.86 POLB (0.51) POLBPOLA1POLD1TK1DTYMK
SCHEMBL5188713 0.84 POLB (0.45) POLBPOLA1POLD1TK1DTYMK
SCHEMBL15515984 0.84 POLB (0.56) POLBPOLA1POLD1TK1DTYMK
SCHEMBL5285301 0.84 POLB (0.48) POLBPOLA1POLD1TK1DTYMK
SCHEMBL26676224 0.83 P2RY6 (0.59) POLA1P2RY6P2RY2P2RY4
SCHEMBL31115953 0.82 POLB (0.47) POLBPOLA1POLD1DTYMKP2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010110775-A1 REAGENTS FOR REVERSIBLY TERMINATING PRIMER EXTENSION BENNER STEVEN ALBERT (US) 2010-09-30 WO disclosed