Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | POLD1 | P28340 | 1/20 | 0.48 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.41 |
| ▸ | DTYMK | P23919 | 2/20 | 0.40 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.40 |
| ▸ | TK1 | P04183 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010795 | 0.90 | P2RY6 (0.41) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL5191085 | 0.89 | POLB (0.50) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL4619794 | 0.85 | P2RY6 (0.55) | POLA1P2RY6P2RY2P2RY4 | |
| SCHEMBL7240891 | 0.84 | POLB (0.52) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL29538414 | 0.84 | POLB (0.51) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL3715513 | 0.84 | POLB (0.51) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL29723202 | 0.84 | POLB (0.51) | POLBPOLA1POLD1P2RY6P2RY2 | |
| SCHEMBL5188713 | 0.83 | POLB (0.45) | POLBPOLA1POLD1P2RY6P2RY2 | |
| Phosphoric Acid SCHEMBL5285296 | 0.83 | TYMP (0.39) | TK1 | |
| SCHEMBL31742537 | 0.83 | POLB (0.51) | POLBPOLA1POLD1P2RY6P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053702-A2 | SYNTHESIS OF FOUR COLOR 3'-O-ALLYL MODIFIED PHOTOCLEAVABLE FLUORESCENT NUCLEOTIDES AND RELATED METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007002204-A2 | PYROSEQUENCING METHODS AND RELATED COMPOSTIONS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-01-04 | — | — | WO | disclosed |