Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.44 |
| ▸ | GPR142 | Q7Z601 | 6/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761090 | 0.81 | RIPK1 (0.47) | RIPK1PIK3CACREBBP | |
| SCHEMBL3789225 | 0.80 | RIPK1 (0.46) | RIPK1GPR142PIK3CACREBBPCYP2D6 | |
| SCHEMBL7968822 | 0.77 | ESR1 (0.44) | ALDH1A1KDM4E | |
| SCHEMBL16634768 | 0.77 | ESR2 (0.44) | ALDH1A1 | |
| SCHEMBL29501124 | 0.76 | RIPK1 (0.54) | RIPK1GPR142PIK3CAALDH1A1KDM4E | |
| SCHEMBL17957763 | 0.76 | RIPK1 (0.54) | RIPK1GPR142PIK3CAALDH1A1KDM4E | |
| SCHEMBL25228696 | 0.76 | HDAC1 (0.43) | ALDH1A1KDM4E | |
| SCHEMBL19644437 | 0.72 | CREBBP (0.60) | GPR142PIK3CACREBBP | |
| SCHEMBL3806238 | 0.72 | ROCK1 (0.45) | RIPK1GPR142PIK3CACREBBP | |
| SCHEMBL4012679 | 0.72 | RIPK1 (0.45) | RIPK1GPR142PIK3CACREBBPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118208-A1 | BENZOXAZEPIN-4- (5H) -YL DERIVATIVES AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |