Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715866 | 1.00 | HCAR2 (0.42) | HCAR2CA2ATMGPR84FFAR1 | |
| SCHEMBL9709099 | 0.85 | HCAR2 (0.38) | HCAR2CA2ATM | |
| SCHEMBL9576185 | 0.84 | MAPT (0.42) | HCAR2ATMGPR84FFAR1ZDHHC7 | |
| SCHEMBL4953193 | 0.84 | TSHR (0.46) | CA2GPR84FFAR1ZDHHC7MAPT | |
| SCHEMBL1321487 | 0.82 | TSHR (0.38) | HCAR2CA2ATM | |
| SCHEMBL1321481 | 0.82 | TSHR (0.38) | HCAR2CA2ATM | |
| SCHEMBL28767432 | 0.82 | CA2 (0.42) | CA2GPR84FFAR1ZDHHC7LMNA | |
| SCHEMBL28731369 | 0.82 | CA2 (0.42) | CA2GPR84FFAR1ZDHHC7LMNA | |
| SCHEMBL5698288 | 0.81 | LMNA (0.58) | LMNAMAPT | |
| SCHEMBL5611572 | 0.80 | HCAR2 (0.49) | HCAR2CA2GPR84FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398874-B1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | LUBRIZOL CORP (US) | 2017-04-26 | — | — | EP | disclosed |
| EP-2398874-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | The Lubrizol Corporation (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010096291-A1 | COMPOUNDS AND A METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |