Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1221721 | 0.82 | KCNH2 (0.37) | MEN1KMT2AMAOBPTGS2ALOX5AP | |
| SCHEMBL1436505 | 0.82 | PPARG (0.42) | ACACBPDK2MAPTTP53SMN1; SMN2 | |
| SCHEMBL1509456 | 0.81 | MAPK8 (0.38) | ACACBPDK2ACACAMAPTTP53 | |
| SCHEMBL3715985 | 0.80 | PDK2 (0.36) | ACACBPDK2ACACASDHBMAPT | |
| SCHEMBL1509397 | 0.79 | MAPK8 (0.37) | ACACBPDK2MAPTTP53SMN1; SMN2 | |
| SCHEMBL1436617 | 0.79 | AKR1C3 (0.44) | MAPTTP53SMN1; SMN2THRATHRB | |
| SCHEMBL1436724 | 0.78 | PPARG (0.41) | ACACBPDK2MAPTTP53SMN1; SMN2 | |
| SCHEMBL1436359 | 0.78 | PPARG (0.37) | ACACBPDK2ACACAMAPTTP53 | |
| SCHEMBL1509419 | 0.78 | AKR1C3 (0.37) | ACACBPDK2MAPTTP53SMN1; SMN2 | |
| SCHEMBL1509213 | 0.78 | PPARG (0.39) | ACACBPDK2MAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081149-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLAXOSMITHKLINE LLC (US) | 2010-07-15 | — | — | WO | disclosed |