SCHEMBL3716084

SCHEMBL3716084

Fc1ccc(CN2CCN(C3CCN(c4ccc(F)cc4)CC3)CC2)cc1

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 10/20 0.71
L3MBTL3 Q96JM7 9/20 0.71
MAPT P10636 1/20 0.64
MBTD1 Q05BQ5 2/20 0.52
TP53BP1 Q12888 2/20 0.52
GAA P10253 1/20 0.52
TSHR P16473 2/20 0.52
DRD2 P14416 1/20 0.51
DRD4 P21917 1/20 0.51
DRD3 P35462 1/20 0.51
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3710413 0.99 L3MBTL1 (0.69) L3MBTL1L3MBTL3MAPTMBTD1TP53BP1
SCHEMBL3711514 0.94 L3MBTL1 (0.67) L3MBTL1L3MBTL3MAPTGAATSHR
Hydrochloric Acid SCHEMBL3708165 0.93 L3MBTL1 (0.65) L3MBTL1L3MBTL3MAPTGAATSHR
Hydrochloric Acid SCHEMBL3716255 0.85 L3MBTL3 (0.71) L3MBTL1L3MBTL3MAPTMBTD1TP53BP1
SCHEMBL16225912 0.84 TSHR (0.62) TSHRDRD2DRD4DRD3
SCHEMBL16225775 0.84 TSHR (0.62) TSHRDRD2DRD4DRD3
SCHEMBL23682967 0.83 L3MBTL3 (1.00) L3MBTL1L3MBTL3MBTD1TP53BP1
SCHEMBL16226678 0.83 MEN1 (0.68) L3MBTL1L3MBTL3MAPTTSHRKDM4E
SCHEMBL3711524 0.82 DRD4 (0.70) L3MBTL1L3MBTL3MAPTMBTD1TP53BP1
SCHEMBL3528306 0.82 L3MBTL3 (0.97) L3MBTL1L3MBTL3MBTD1TP53BP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010081851-A1 PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION GENOSCIENCE PHARMA (FR) 2010-07-22 WO disclosed