Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712550 | 0.83 | HCAR3 (0.42) | ESR1SYKNQO2IDH1 | |
| SCHEMBL30060544 | 0.80 | NQO2 (0.40) | ESR1HRH4SYKNQO2IDH1 | |
| SCHEMBL27172368 | 0.80 | NQO2 (0.40) | ESR1HRH4SYKNQO2IDH1 | |
| SCHEMBL25389725 | 0.80 | ESR1 (0.46) | ESR1SYKNQO2IDH1LMNA | |
| SCHEMBL3715043 | 0.80 | HRH4 (0.46) | ESR1HRH4ALOX5PPARGNPSR1 | |
| SCHEMBL19072400 | 0.79 | KMT2A (0.45) | ESR1PPARGSYKNQO2IDH1 | |
| SCHEMBL27204883 | 0.77 | MTNR1A (0.41) | SYKGAA | |
| SCHEMBL11925474 | 0.77 | CXCR2 (0.44) | ESR1SYKNQO2IDH1FPR2 | |
| SCHEMBL512745 | 0.76 | NQO2 (0.44) | SYKNQO2NPSR1LMNA | |
| SCHEMBL30060495 | 0.76 | NQO2 (0.38) | ESR1SYKNQO2IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |