Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.71 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.61 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pyrrolidone SCHEMBL28888242 | 0.98 | OR51E2 (0.68) | OR51E2CRBNFKBP5GAAKDM4E | |
| Dioxane SCHEMBL28901631 | 0.93 | OR51E2 (0.75) | OR51E2CRBNFKBP5GAAKDM4E | |
| Caprolactam SCHEMBL27960153 | 0.91 | CRBN (0.70) | OR51E2CRBNFKBP5GAAKDM4E | |
| 2-Pyrrolidone SCHEMBL28283119 | 0.90 | — | — | |
| 2-Pyrrolidone SCHEMBL4300422 | 0.87 | — | — | |
| Morpholine SCHEMBL28108320 | 0.86 | OR51E2 (0.65) | OR51E2CRBNFKBP5GAAKDM4E | |
| SCHEMBL23459791 | 0.86 | — | — | |
| SCHEMBL12092486 | 0.86 | CRBN (0.61) | OR51E2CRBNFKBP5GAAKDM4E | |
| 2-Pyrrolidone SCHEMBL28862005 | 0.85 | OR51E2 (0.88) | OR51E2CRBNFKBP5GAAKDM4E | |
| 2-Pyrrolidone SCHEMBL4299593 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105899487-B | Method for producing 5-hydroxypiperidine-2-carboxylic acid | 株式会社API | 2018-10-19 | — | — | CN | disclosed |
| CN-105924644-A | Polyarylsulfone and preparation method thereof | 中国科学院长春应用化学研究所 | 2016-09-07 | — | — | CN | disclosed |
| CN-105899487-A | Method for producing 5-hydroxypiperidine-2-carboxylic acid | 株式会社API | 2016-08-24 | — | — | CN | disclosed |
| WO-2010111755-A2 | IMPROVED METHOD FOR MAKING CROSS-LINKED POLYIMIDE MEMBRANES | KATHOLIEKE UNIVERSITEIT LEUVEN - K.U.LEUVEN R & D (BE) | 2010-10-07 | — | — | WO | disclosed |