Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718102 | 1.00 | SLC2A1 (0.38) | SLC2A1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL3711185 | 0.99 | SLC2A1 (0.38) | SLC2A1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL3713064 | 0.98 | SLC2A1 (0.38) | SLC2A1S1PR1S1PR3S1PR4S1PR5 | |
| Tromethamine SCHEMBL3709545 | 0.93 | S1PR1 (0.42) | S1PR1S1PR3 | |
| SCHEMBL3723682 | 0.86 | DGAT1 (0.37) | S1PR1S1PR3 | |
| SCHEMBL3718803 | 0.85 | AR (0.39) | SLC2A1PTGER4TRPV1AR | |
| SCHEMBL3110262 | 0.84 | SLC2A1 (0.43) | SLC2A1PTGER4MMP2MMP9MMP8 | |
| SCHEMBL3561339 | 0.81 | SLC2A1 (0.40) | SLC2A1MMP2MMP9MMP8 | |
| SCHEMBL4472453 | 0.80 | SLC2A1 (0.58) | SLC2A1MMP2MMP9MMP8 | |
| Potassium Ion SCHEMBL3713067 | 0.78 | PTGER4 (0.33) | SLC2A1S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094738-A1 | PHOSPHATE ESTER OF A 4-PYRIDONE DERIVATIVE AND ITS USE IN THE CHEMOTHERAPY OF PARASITIC INFECTIONS | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |