Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 9/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13049103 | 0.87 | SCN10A (0.37) | DGAT1S1PR1S1PR3SCN10ASCN2A | |
| SCHEMBL13049774 | 0.87 | DGAT1 (0.40) | DGAT1SCN10AKCNH2SCN2AMAT2A | |
| SCHEMBL3711185 | 0.87 | SLC2A1 (0.38) | S1PR1S1PR3 | |
| SCHEMBL3718102 | 0.86 | SLC2A1 (0.38) | S1PR1S1PR3 | |
| SCHEMBL3716508 | 0.86 | SLC2A1 (0.38) | S1PR1S1PR3 | |
| SCHEMBL3713064 | 0.86 | SLC2A1 (0.38) | S1PR1S1PR3 | |
| SCHEMBL4490712 | 0.83 | SLC2A1 (0.40) | DGAT1SCN10AKCNH2SCN2AMAT2A | |
| Hydrochloric Acid SCHEMBL4489660 | 0.82 | DGAT1 (0.39) | DGAT1SCN10AKCNH2SCN2AMAT2A | |
| Tromethamine SCHEMBL3709545 | 0.81 | S1PR1 (0.42) | S1PR1S1PR3 | |
| SCHEMBL3717418 | 0.80 | DGAT1 (0.39) | DGAT1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142741-A1 | PHENYLPYRIDYLPYRIDONES FOR USE AS ANTIMALARIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2010-12-16 | — | — | WO | claimed |
| WO-2010142741-A1 | PHENYLPYRIDYLPYRIDONES FOR USE AS ANTIMALARIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142741-A1 | PHENYLPYRIDYLPYRIDONES FOR USE AS ANTIMALARIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |