Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2745550 | 0.85 | GFER (0.42) | TAAR1GFERESR1ESR2 | |
| SCHEMBL9552515 | 0.82 | GFER (0.47) | TAAR1GFERESR1ESR2 | |
| SCHEMBL1338455 | 0.78 | HRH3 (0.35) | TAAR1GFERESR1ESR2 | |
| SCHEMBL656449 | 0.78 | TAAR1 (0.56) | TAAR1 | |
| SCHEMBL15553460 | 0.74 | GFER (0.35) | GFERESR1ESR2 | |
| SCHEMBL839424 | 0.72 | TAAR1 (0.56) | TAAR1 | |
| SCHEMBL7525993 | 0.72 | HRH3 (0.52) | TAAR1GFER | |
| SCHEMBL21540700 | 0.72 | TAAR1 (0.64) | TAAR1 | |
| SCHEMBL1610768 | 0.72 | LPL (0.50) | TAAR1ESR1 | |
| SCHEMBL5537656 | 0.72 | MAOB (0.56) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010131146-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2010131147-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2010131145-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2010131145-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010131147-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |