SCHEMBL839424

SCHEMBL839424

[CH2]CCc1ccc(Br)cc1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.56
HTR2A P28223 1/20 0.56
CYP2A6 P11509 1/20 0.44
IDO1 P14902 3/20 0.42
POLB P06746 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
PYCR1 P32322 1/20 0.38
TGM2 P21980 1/20 0.36
HMOX1 P09601 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28582932 0.91 TAAR1 (0.48) TAAR1HTR2ACYP2A6IDO1POLB
SCHEMBL10439490 0.87 TAAR1 (0.45) TAAR1HTR2AIDO1PYCR1TGM2
SCHEMBL2745550 0.85 GFER (0.42) TAAR1HTR2ACYP2A6
SCHEMBL1005011 0.84 TAAR1 (0.52) TAAR1HTR2ACYP2A6IDO1HMOX1
SCHEMBL1046202 0.82 TAAR1 (0.50) TAAR1HTR2ACYP2A6IDO1HMOX1
SCHEMBL626076 0.82 TAAR1 (0.68) TAAR1HTR2ACYP2A6IDO1POLB
SCHEMBL1045906 0.80 TAAR1 (0.48) TAAR1HTR2ACYP2A6IDO1HMOX1
SCHEMBL15351972 0.80 TAAR1 (0.48) TAAR1HTR2ACYP2A6IDO1HMOX1
SCHEMBL15352000 0.80 TAAR1 (0.48) TAAR1HTR2ACYP2A6IDO1HMOX1
SCHEMBL15352255 0.80 TAAR1 (0.48) TAAR1HTR2ACYP2A6IDO1HMOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117384079-B Chiral N-alkyl indole compound and preparation method and application thereof 云南大学 2024-05-24 CN claimed
CN-117384079-A Chiral N-alkyl indole compound and preparation method and application thereof 云南大学 2024-01-12 CN claimed
CN-101993416-A Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound SHANGHAI INST MATERIA MEDICA 2011-03-30 CN claimed
US-20240239922-A1 PHOTOCURABLE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-07-18 US disclosed
US-20240191003-A1 COMPOSITION AND PHOTOSENSITIVE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-06-13 US disclosed
US-20240192593-A1 PHOTOSENSITIVE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-06-13 US disclosed
CN-117384079-B Chiral N-alkyl indole compound and preparation method and application thereof 云南大学 2024-05-24 CN disclosed
CN-117999296-A Composition and photosensitive composition 东京应化工业株式会社 2024-05-07 CN disclosed
CN-117980346-A Composition and photosensitive composition 东京应化工业株式会社 2024-05-03 CN disclosed
CN-117980347-A Photosensitive composition 东京应化工业株式会社 2024-05-03 CN disclosed
US-20240141085-A1 PHOTOCURABLE LIQUID COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING CURED PRODUCT TOKYO OHKA KOGYO CO., LTD. (JP) 2024-05-02 US disclosed
US-4409220-A Fused-ring amino-pyrazines as bradycardiac agents DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-10-11 US disclosed
EP-0024943-B1 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM TORAY INDUSTRIES, INC. (JP) 1983-08-17 EP disclosed
US-4372953-A Tetrazole derivatives, and anti-ulcer composition containing the same OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1983-02-08 US disclosed
US-4343811-A ATHEROSCLEROSIS BOEHRINGER INGELHEIM GMBH (DE) 1982-08-10 US disclosed
US-4301164-A FOR USE AS ANTIULCER AGENTS, HYPOTENSIVE AGENTS, ANTITHROMBOSIC AGENTS TORAY INDUSTRIES, INC. (JP) 1981-11-17 US disclosed
EP-0035228-A1 Tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1981-09-09 EP disclosed
EP-0024943-A1 5,6,7-Trinor-4,8-inter-m-phenylene PGI2 derivatives and pharmaceutical compositions containing them TORAY INDUSTRIES, INC. (JP) 1981-03-11 EP disclosed
US-4024141-A HERBICIDES CHEVRON RESEARCH COMPANY (US) 1977-05-17 US disclosed
US-3938985-A HERBICIDE CHEVRON RESEARCH COMPANY (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240192593-A1 PHOTOSENSITIVE COMPOSITION PPOX, ERCC1, ERCC5 TAAR1 4449/4885HTR2A 2543/4885CYP2A6 3568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.