Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 3/20 | 0.44 |
| ▸ | GABRD | O14764 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.44 |
| ▸ | GABRE | P78334 | 3/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17495632 | 0.89 | NR4A2 (0.60) | NR4A2F7F3AVPR1AGPR84 | |
| SCHEMBL2535534 | 0.87 | F7 (0.71) | NR4A2F7F3GABRPGABRD | |
| SCHEMBL26204498 | 0.87 | NR4A2 (0.65) | NR4A2F7F3AVPR1AGPR84 | |
| SCHEMBL7538181 | 0.85 | NR4A2 (0.63) | NR4A2F7F3AVPR1AGPR84 | |
| SCHEMBL840574 | 0.85 | NR4A2 (0.63) | NR4A2F7F3AVPR1AGPR84 | |
| SCHEMBL30392504 | 0.83 | F7 (0.74) | NR4A2F7F3AVPR1AGPR84 | |
| SCHEMBL613332 | 0.83 | F7 (0.74) | NR4A2F7F3AVPR1AGPR84 | |
| Ammonia Solution, Strong SCHEMBL4556453 | 0.81 | F7 (0.72) | NR4A2F7F3AVPR1AGPR84 | |
| SCHEMBL24143372 | 0.81 | CYP2A6 (0.49) | NR4A2ALDH1A1MEN1KMT2AATM | |
| SCHEMBL3714231 | 0.81 | NR4A2 (0.63) | NR4A2ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |