Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725153 | 0.87 | NR4A2 (0.63) | NR4A2RAB9AKDM4EHSD17B10LMNA | |
| SCHEMBL16205922 | 0.87 | NR4A2 (0.67) | NR4A2RAB9AKDM4EHSD17B10LMNA | |
| SCHEMBL1558890 | 0.85 | NR4A2 (0.65) | NR4A2RAB9AKDM4EHSD17B10LMNA | |
| SCHEMBL23551182 | 0.84 | NR4A2 (0.63) | NR4A2RAB9AKDM4EHSD17B10LMNA | |
| SCHEMBL2659416 | 0.83 | NR4A2 (0.71) | NR4A2RAB9AKDM4EHSD17B10LMNA | |
| SCHEMBL17032685 | 0.81 | NR4A2 (0.69) | NR4A2RAB9AKDM4EHSD17B10LMNA | |
| SCHEMBL6029944 | 0.81 | NR4A2 (0.73) | NR4A2RAB9AKDM4EHSD17B10LMNA | |
| SCHEMBL3716737 | 0.81 | NR4A2 (0.61) | NR4A2ALDH1A1ATM | |
| SCHEMBL3714077 | 0.81 | TDO2 (0.50) | KDM4EHTR2AALDH1A1ATM | |
| SCHEMBL24143372 | 0.81 | CYP2A6 (0.49) | NR4A2ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219501-A1 | COMPOUND CONTAINING 2,4-THIAZOLE RING, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shandong University (CN) | 2023-08-02 | — | — | EP | disclosed |
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |