SCHEMBL3716873

SCHEMBL3716873

O=P(Oc1ccccc1)(Oc1ccccc1)Oc1onc2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.38
L3MBTL1 Q9Y468 4/20 0.37
TDP1 Q9NUW8 1/20 0.37
KDM4E B2RXH2 3/20 0.35
KMT2A Q03164 3/20 0.35
GLA P06280 1/20 0.35
MAPT P10636 1/20 0.35
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
IP6K1 Q92551 2/20 0.34
IP6K3 Q96PC2 2/20 0.34
IP6K2 Q9UHH9 2/20 0.34
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31301176 0.76 MAPT (0.50) KDM4EKMT2AGLAMAPTTSHR
Triphenyl Phosphate SCHEMBL28761613 0.73 SRC (0.64) SRCL3MBTL1TDP1KDM4EKMT2A
Triphenyl Phosphate SCHEMBL28557783 0.73 SRC (0.64) SRCL3MBTL1TDP1KDM4EKMT2A
Triphenyl Phosphate SCHEMBL18116 0.73 SRC (0.64) SRCL3MBTL1TDP1KDM4EKMT2A
Triphenyl Phosphate SCHEMBL483692 0.73 SRC (0.64) SRCL3MBTL1TDP1KDM4EKMT2A
SCHEMBL2441052 0.72 FAAH (0.42) SRCL3MBTL1TDP1MAPTLMNA
Triphenyl Phosphate SCHEMBL15815456 0.71 SRC (0.61) SRCL3MBTL1TDP1KDM4EKMT2A
SCHEMBL131239 0.71 CYP3A4 (0.61) SRCL3MBTL1TDP1KDM4EKMT2A
Triphenyl Phosphate SCHEMBL1924512 0.71 SRC (0.61) SRCL3MBTL1TDP1KDM4EKMT2A
Triphenyl Phosphate SCHEMBL2530073 0.71 SRC (0.61) SRCL3MBTL1TDP1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1869063-A2 METHODS OF MANUFACTURING BIOACTIVE 3-ESTERS OF BETULINIC ALDEHYDE AND BETULINIC ACID REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2007-12-26 EP claimed
WO-2006105356-A2 METHODS OF MANUFACTURING BIOACTIVE 3-ESTERS OF BETULINIC ALDEHYDE AND BETULINIC ACID REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2006-10-05 WO claimed
EP-3980057-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF Institut Curie (FR) 2022-04-13 EP disclosed
WO-2020245321-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2020-12-10 WO disclosed
EP-3265109-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES Stealth BioTherapeutics Corp (MC) 2018-01-10 EP disclosed
WO-2016144905-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS CORP (MC) 2016-09-15 WO disclosed
EP-2398774-A2 PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS Incyte Corporation (US) 2011-12-28 EP disclosed
WO-2010083283-A2 PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS INCYTE CORPORATION (US) 2010-07-22 WO disclosed
EP-1658080-A1 DOSING SCHEDULE FOR A ERBB2 ANTICANCER AGENTS Pfizer Products Inc. (US) 2006-05-24 EP disclosed
WO-2005016347-A1 DOSING SCHEDULE FOR ERBB2 ANTICANCER AGENTS PFIZER PRODUCTS INC. (US) 2005-02-24 WO disclosed