Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.41 |
| ▸ | IP6K3 | Q96PC2 | 3/20 | 0.41 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716873 | 0.76 | SRC (0.38) | MAPTKMT2AKDM4EGLAHTT | |
| SCHEMBL2490792 | 0.76 | POLB (0.45) | MAPTKMT2AKDM4ELMNARAB9A | |
| SCHEMBL2494284 | 0.72 | ELANE (0.45) | MAPTKMT2AKDM4EHTTTSHR | |
| SCHEMBL29034525 | 0.70 | LTA4H (0.52) | MAPTKMT2AKDM4EGLAHTT | |
| SCHEMBL7144568 | 0.69 | KMT2A (0.33) | KMT2ALMNATSHRRAB9AALDH1A1 | |
| SCHEMBL11443235 | 0.68 | MAOA (0.41) | MAPTKMT2AKDM4EGLAHTT | |
| SCHEMBL31001160 | 0.68 | ALDH1A1 (0.46) | MAPTKMT2AKDM4EGLAHTT | |
| SCHEMBL455804 | 0.67 | KDM4E (1.00) | MAPTKMT2AKDM4EGLAHTT | |
| SCHEMBL2492556 | 0.65 | ALDH1A1 (0.62) | MAPTKMT2AKDM4EHTTLMNA | |
| SCHEMBL9035692 | 0.65 | FAAH (0.49) | MAPTKMT2AKDM4EGLAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | CGAS, TDP1, CYP11B2 | MAPT 245/4885KMT2A 4398/4885KDM4E 4732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.