Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 17/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719464 | 0.90 | SLC9A1 (0.54) | SLC9A1KDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL3711949 | 0.82 | SLC9A1 (0.56) | SLC9A1KDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL3710586 | 0.80 | SLC9A1 (0.58) | SLC9A1KDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL4943762 | 0.79 | ABCB1 (0.48) | SLC9A1ABCB1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3707944 | 0.79 | SLC9A1 (0.52) | SLC9A1KDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL3713926 | 0.77 | SLC9A1 (0.61) | SLC9A1KDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL3712694 | 0.77 | SLC9A1 (0.61) | SLC9A1ALDH1A1MAPT | |
| SCHEMBL4943767 | 0.77 | SLC9A1 (0.79) | SLC9A1 | |
| SCHEMBL3786003 | 0.76 | SLC9A1 (0.57) | SLC9A1ALDH1A1HPGD | |
| SCHEMBL3711899 | 0.76 | SLC9A1 (0.59) | SLC9A1KDM4EALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | claimed |
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | disclosed |