Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 14/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711949 | 0.85 | SLC9A1 (0.56) | SLC9A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3795202 | 0.84 | SLC9A1 (0.61) | SLC9A1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3788349 | 0.83 | SLC9A1 (0.55) | SLC9A1KDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3710904 | 0.81 | SLC9A1 (0.56) | SLC9A1KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL3722093 | 0.80 | SLC9A1 (0.54) | SLC9A1SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL3712980 | 0.80 | SLC9A1 (0.56) | SLC9A1KDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3717422 | 0.79 | SLC9A1 (0.48) | SLC9A1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3711058 | 0.79 | SLC9A1 (0.53) | SLC9A1KDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3709712 | 0.78 | SLC9A1 (0.56) | SLC9A1KDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3786003 | 0.78 | SLC9A1 (0.57) | SLC9A1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | claimed |
| WO-2010094090-A2 | SYNUCLEINOPATHIES | KATHOLLEKE UNIVERSITEIT LEUVEN (BE) | 2010-08-26 | — | — | WO | disclosed |