Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | NOS2 | P35228 | 3/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3717716 | 0.99 | TAAR1 (0.48) | TAAR1NOS2FNTAFNTBPGGT1B | |
| SCHEMBL5338713 | 0.82 | FNTA (0.50) | NOS2FNTAFNTBPGGT1BAR | |
| Hydrochloric Acid SCHEMBL5345494 | 0.81 | FNTA (0.49) | NOS2FNTAFNTBPGGT1BAR | |
| SCHEMBL1197429 | 0.77 | CYP1A2 (0.57) | NOS2ARCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL11190089 | 0.77 | AR (0.47) | NOS2FNTAFNTBPGGT1BAR | |
| SCHEMBL3717713 | 0.76 | PTGDR2 (0.40) | NOS2FNTAFNTBPGGT1BAR | |
| SCHEMBL9889572 | 0.75 | AR (0.48) | TAAR1FNTAFNTBPGGT1BAR | |
| SCHEMBL5357366 | 0.74 | SLC6A4 (0.56) | NOS2FNTAFNTBPGGT1BCYP2D6 | |
| SCHEMBL2805226 | 0.74 | NOS2 (0.47) | NOS2FNTAFNTBPGGT1BAR | |
| SCHEMBL5348856 | 0.73 | SLC6A4 (0.49) | TAAR1NOS2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108059-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS ANTAGONISTS OF THE HISTAMINE H4 RECEPTOR | INCYTE CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |