Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | F2R | P25116 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 2/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726373 | 0.82 | ACACB (0.35) | HRH3PDGFRBPDGFRAABL1SRC | |
| SCHEMBL3717609 | 0.82 | ACACB (0.33) | HRH3PDGFRBPDGFRAPDE3BPDE3A | |
| SCHEMBL3726370 | 0.81 | PDE4B (0.47) | HRH3ABL1SRCMAOBMAOA | |
| SCHEMBL3724497 | 0.81 | CSNK2A1 (0.35) | HRH3 | |
| SCHEMBL3724494 | 0.81 | MAOA (0.33) | HRH3PDGFRBPDGFRAABL1SRC | |
| SCHEMBL13077244 | 0.76 | ACACB (0.50) | — | |
| SCHEMBL3721867 | 0.70 | SCN7A (0.37) | HPGD | |
| SCHEMBL3721927 | 0.68 | PARP10 (0.37) | HPGDMAOBMAOAPPARD | |
| SCHEMBL677293 | 0.67 | HPGD (0.50) | HPGD | |
| SCHEMBL3722666 | 0.66 | MAOA (0.37) | HPGDMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |