SCHEMBL3722666

SCHEMBL3722666

CCNc1ccc2nc(Oc3ccc(OCC4CCCCC4)cc3C)ccc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
PARP15 Q460N3 2/20 0.35
PARP10 Q53GL7 2/20 0.35
MAPT P10636 1/20 0.35
F2RL3 Q96RI0 1/20 0.35
CCNB2 O95067 2/20 0.34
CDK1 P06493 2/20 0.34
CCNB1 P14635 2/20 0.34
CCNA2 P20248 2/20 0.34
CDK2 P24941 2/20 0.34
CCNA1 P78396 2/20 0.34
CCNB3 Q8WWL7 2/20 0.34
GPR119 Q8TDV5 1/20 0.33
SYK P43405 1/20 0.33
ELANE P08246 1/20 0.33
MCHR1 Q99705 3/20 0.33
ACACB O00763 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3719458 0.90 PARP15 (0.37) MAOAMAOBPARP15PARP10MAPT
SCHEMBL3717024 0.88 SCN7A (0.38) MAOAMAOBPARP15PARP10MAPT
SCHEMBL3724494 0.85 MAOA (0.33) MAOAMAOBMAPTF2RL3GPR119
SCHEMBL3718624 0.85 ACACB (0.46) MAPTACACBCYP3A4CYP2C9ACACA
SCHEMBL3721905 0.84 EPHA2 (0.38) CCNB2CDK1CCNB1CCNA2CDK2
SCHEMBL3720374 0.84 EGFR (0.34) PARP15PARP10MAPTCCNB2CDK1
SCHEMBL3720645 0.83 MAPT (0.39) MAPTACACBCYP3A4ACACA
SCHEMBL3720087 0.83 MAPT (0.38) MAPTACACBACACA
SCHEMBL3797155 0.81 MTNR1A (0.42) MAPTMCHR1ACACBCYP3A4CYP2C9
SCHEMBL3720723 0.81 MAPT (0.44) MAOAMAOBMAPTELANEACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010127208-A1 INHIBITORS OF ACETYL-COA CARBOXYLASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2010-11-04 WO disclosed