⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385199 | 0.69 | — | — | |
| SCHEMBL30707297 | 0.65 | GABRP (0.31) | — | |
| SCHEMBL3717746 | 0.60 | — | — | |
| SCHEMBL3706343 | 0.59 | — | — | |
| SCHEMBL3505396 | 0.58 | — | — | |
| SCHEMBL10591278 | 0.58 | — | — | |
| SCHEMBL604100 | 0.57 | — | — | |
| SCHEMBL10921873 | 0.57 | — | — | |
| SCHEMBL27266037 | 0.57 | — | — | |
| SCHEMBL10956840 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101563328-B | substituted heteroaryl Pyridopyrimidinone derivatives | SANOFI AVENTIS | 2012-03-14 | — | — | CN | claimed |
| WO-2010086387-A1 | 5-HT4 INHIBITORS FOR TREATING AIRWAY DISEASES, IN PARTICULAR ASTHMA | MOVETIS NV (BE) | 2010-08-05 | — | — | WO | claimed |
| CN-101563328-A | Substituted heteroaryl pyridopyrimidinone derivatives | SANOFI AVENTIS (FR) | 2009-10-21 | — | — | CN | claimed |
| CN-101563328-B | substituted heteroaryl Pyridopyrimidinone derivatives | SANOFI AVENTIS | 2012-03-14 | — | — | CN | disclosed |
| CN-102300572-A | 5-HT4 inhibitors for treating airway diseases, in particular asthma | — | 2011-12-28 | — | — | CN | disclosed |
| CN-101563328-A | Substituted heteroaryl pyridopyrimidinone derivatives | SANOFI AVENTIS (FR) | 2009-10-21 | — | — | CN | disclosed |
| WO-2003080564-A1 | MENTHOL SUBSTITUTED ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |