SCHEMBL604100

SCHEMBL604100

O=C(O)C1=CCOC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL17114599 0.89
SCHEMBL1373713 0.87
Piperidine SCHEMBL22556777 0.86 TSHR (0.33)
SCHEMBL9751986 0.84
SCHEMBL1433046 0.80
SCHEMBL2241122 0.80
Hydrochloric Acid SCHEMBL12479156 0.78
SCHEMBL8132933 0.77 ALDH1A1 (0.45)
SCHEMBL6205702 0.71 TP53 (0.36)
SCHEMBL3717746 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3759113-B1 10-(DI(PHENYL)METHYL)-4-HYDROXY-8,9,9A,10-TETRAHYDRO-7H-PYRROLO[1',2':4,5]PYRAZINO[1,2-B]PYRIDAZINE-3,5-DIONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE ORTHOMYXOVIRUS REPLICATION FOR TREATING INFLUENZA NOVARTIS AG (CH) 2024-09-11 EP claimed
CN-117705184-A Detection method for chemical components of anemone-resistant tung tree 中国热带农业科学院热带作物品种资源研究所 2024-03-15 CN claimed
CN-102151282-A Application of iridoid glycoside and derivatives thereof as plasmin inhibitor and medicine composites of plasmin inhibitor ZHENGPING JIA 2011-08-17 CN claimed
EP-1181017-A1 METALLOPROTEASE INHIBITORS Pfizer Limited (GB) 2002-02-27 EP claimed
WO-2000074681-A1 METALLOPROTEASE INHIBITORS PFIZER LIMITED (GB) 2000-12-14 WO claimed
CN-122070276-A Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same 人类生物科学股份有限公司 2026-05-19 CN disclosed
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2026-04-30 US disclosed
CN-121779365-A Synthesis method of 4-aminotetralin-2H-pyran-4-formic acid 宁波人健化学制药有限公司 2026-04-03 CN disclosed
EP-4705289-A1 PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF Terran Biosciences Inc. (US) 2026-03-11 EP disclosed
EP-4706671-A2 CONJUGATED HEPCIDIN MIMETICS Protagonist Therapeutics, Inc. (US) 2026-03-11 EP disclosed
EP-3570864-B1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2026-02-18 EP disclosed
US-12552836-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases PROTAGONIST THERAPEUTICS, INC. (US) 2026-02-17 US disclosed
EP-0787127-B1 5-LIPOXYGENASE INHIBITORS PFIZER (US) 2001-01-03 EP disclosed
EP-0992510-A1 N6 heterocyclic substituted adenosine derivatives CV THERAPEUTICS, INC. (US) 2000-04-12 EP disclosed
US-6022888-A Iridoid derivatives and neovascularization inhibitors containing the same as active ingredient TSUMURA & CO. (JP) 2000-02-08 US disclosed
EP-0920438-A2 N6 HETEROCYCLIC SUBSTITUTED ADENOSINE DERIVATIVES CV THERAPEUTICS, INC. (US) 1999-06-09 EP disclosed
US-5789416-A CARDIOVASCULAR AND NERVOUS SYSTEM DISORDERS CV THERAPEUTICS (US) 1998-08-04 US disclosed
WO-1998008855-A2 N6 HETEROCYCLIC SUBSTITUTED ADENOSINE DERIVATIVES CV THERAPEUTICS, INC. (US) 1998-03-05 WO disclosed
EP-0787127-A1 5-LIPOXYGENASE INHIBITORS PFIZER INC. (US) 1997-08-06 EP disclosed
WO-1996011911-A1 5-LIPOXYGENASE INHIBITORS PFIZER INC. (US) 1996-04-25 WO disclosed