Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.58 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3530063 | 0.88 | ALDH1A1 (0.47) | CXCR2 | |
| SCHEMBL22198065 | 0.78 | CXCR2 (0.67) | CXCR2PLK1 | |
| SCHEMBL24137170 | 0.73 | CXCR2 (0.66) | CXCR2PLK1 | |
| SCHEMBL3723764 | 0.73 | PLK1 (0.57) | CXCR2CXCR1PLK1 | |
| SCHEMBL3793190 | 0.71 | GAA (0.62) | CXCR2CXCR1 | |
| SCHEMBL19956913 | 0.69 | CXCR2 (0.56) | CXCR2PLK1 | |
| SCHEMBL19808351 | 0.68 | PLK1 (0.60) | CXCR2PLK1 | |
| SCHEMBL6550194 | 0.68 | CXCR2 (0.67) | CXCR2 | |
| SCHEMBL27249148 | 0.67 | CXCR2 (0.63) | CXCR2PLK1 | |
| SCHEMBL10094591 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010131146-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |