Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713020 | 0.91 | PIK3CD (0.41) | MMP2MMP8MMP13PIK3CD | |
| SCHEMBL3709482 | 0.90 | CCNC (0.42) | MMP2MMP8MMP13PIK3CD | |
| SCHEMBL3714355 | 0.88 | MMP2 (0.42) | MMP2MMP8MMP13HDAC3HDAC1 | |
| SCHEMBL3713224 | 0.86 | JAK2 (0.41) | MMP2MMP8MMP13PIK3CD | |
| SCHEMBL3714557 | 0.83 | HDAC3 (0.47) | MMP2MMP8MMP13HDAC3HDAC1 | |
| SCHEMBL3715125 | 0.82 | CCNC (0.42) | — | |
| SCHEMBL13188524 | 0.81 | HDAC1 (0.46) | PIK3CDHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3710999 | 0.81 | CCNC (0.41) | MMP2MMP8MMP13 | |
| SCHEMBL3721418 | 0.80 | CCNC (0.41) | — | |
| SCHEMBL13188416 | 0.79 | HRH3 (0.48) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |