Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406549 | 0.82 | MAPK1 (0.51) | MAPK1THRBMAPTNPSR1LMNA | |
| SCHEMBL3713558 | 0.74 | CYP1A2 (0.42) | MAPTNPSR1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL3711750 | 0.72 | HTR2A (0.40) | MAPTALDH1A1HPGD | |
| SCHEMBL16519819 | 0.72 | MAPK1 (0.74) | MAPK1THRBALDH1A1POLBL3MBTL1 | |
| SCHEMBL10192850 | 0.72 | MAPK1 (0.46) | MAPK1THRBLMNASCN9ASCN10A | |
| SCHEMBL10382418 | 0.69 | MAPK1 (0.53) | MAPK1THRBMAPTNPSR1LMNA | |
| SCHEMBL10195117 | 0.69 | MAPK1 (0.45) | MAPK1THRBMAPTNPSR1LMNA | |
| SCHEMBL9108246 | 0.69 | LMNA (0.63) | MAPK1THRBMAPTNPSR1LMNA | |
| SCHEMBL11351938 | 0.68 | MAPT (0.69) | MAPK1THRBMAPTNPSR1LMNA | |
| SCHEMBL9255996 | 0.68 | MAPK1 (0.74) | MAPK1THRBMAPTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393796-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089211-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-12 | — | — | WO | disclosed |