Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310216 | 0.81 | ALDH1A1 (0.75) | ALDH1A1KDM4EMAPTMAPK1TRPA1 | |
| SCHEMBL1310214 | 0.81 | ALDH1A1 (0.75) | ALDH1A1KDM4EMAPTMAPK1TRPA1 | |
| SCHEMBL2349983 | 0.78 | TYR (0.61) | ALDH1A1KDM4EMAPTMAPK1TRPA1 | |
| SCHEMBL21402627 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTMAPK1TRPA1 | |
| SCHEMBL2833821 | 0.78 | TYR (0.61) | ALDH1A1KDM4EMAPTMAPK1TRPA1 | |
| SCHEMBL628222 | 0.77 | TYR (0.58) | ALDH1A1KDM4ETYRPTGS2 | |
| SCHEMBL7751067 | 0.75 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTMAPK1TRPA1 | |
| P-Hydroxycinnamaldehyde SCHEMBL20912952 | 0.75 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTMAPK1TRPA1 | |
| P-Hydroxycinnamaldehyde SCHEMBL196960 | 0.75 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTMAPK1TRPA1 | |
| SCHEMBL10299738 | 0.75 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTMAPK1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923734-A1 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | Trega Biosciences, Inc. (US) | 1999-06-23 | — | — | EP | claimed |
| WO-1998002741-A1 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-01-22 | — | — | WO | claimed |
| WO-2013032016-A1 | CELLULOSE ACYLATE FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2013-03-07 | — | — | WO | disclosed |
| WO-2010127381-A1 | DIAGNOSIS, MONITORING, PROGNOSIS, PREVENTION AND TREATMENT OF ANEURYSMS | JAMES COOK UNIVERSITY (AU) | 2010-11-11 | — | — | WO | disclosed |