Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 11/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631800 | 0.97 | RBP4 (0.67) | RBP4KMT2AMEN1POLBLMNA | |
| SCHEMBL3718601 | 0.88 | RBP4 (0.69) | RBP4KMT2AMEN1POLBLMNA | |
| SCHEMBL766272 | 0.88 | RBP4 (0.75) | RBP4KMT2AMEN1POLBLMNA | |
| SCHEMBL766323 | 0.85 | RBP4 (0.87) | RBP4KMT2AMEN1POLBLMNA | |
| SCHEMBL630919 | 0.84 | RBP4 (1.00) | RBP4KMT2AMEN1POLBLMNA | |
| SCHEMBL631691 | 0.84 | RBP4 (0.81) | RBP4KMT2AMEN1POLBLMNA | |
| SCHEMBL631907 | 0.83 | RBP4 (0.75) | RBP4KMT2AMEN1POLBLMNA | |
| SCHEMBL766305 | 0.83 | RBP4 (0.71) | RBP4KMT2AMEN1POLBLMNA | |
| SCHEMBL3723299 | 0.83 | RBP4 (0.74) | RBP4KMT2AMEN1POLBMAPT | |
| SCHEMBL766204 | 0.83 | RBP4 (0.79) | RBP4KMT2AMEN1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459209-A | Derivatives of N-acyl-N' -phenylpiperazines for the prevention or treatment of diabetes (etc.) | TAKEDA PHARMACEUTICAL | 2012-05-16 | — | — | CN | disclosed |
| WO-2010119992-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |