Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 7/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | GOT1 | P17174 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723297 | 0.89 | RBP4 (0.71) | RBP4MEN1KMT2ATRPV1CA2 | |
| SCHEMBL30996953 | 0.86 | RBP4 (1.00) | RBP4MEN1KMT2ATRPV1POLB | |
| SCHEMBL630718 | 0.86 | RBP4 (1.00) | RBP4MEN1KMT2ATRPV1POLB | |
| SCHEMBL631664 | 0.85 | RBP4 (0.83) | RBP4MEN1KMT2ATRPV1CA2 | |
| SCHEMBL766225 | 0.84 | RBP4 (0.73) | RBP4MEN1KMT2ATRPV1CA2 | |
| SCHEMBL766179 | 0.83 | RBP4 (0.72) | RBP4MEN1KMT2ATRPV1CA2 | |
| SCHEMBL631074 | 0.83 | RBP4 (0.69) | RBP4MEN1KMT2ATRPV1CA2 | |
| SCHEMBL630971 | 0.83 | RBP4 (0.72) | RBP4MEN1KMT2ATRPV1CA2 | |
| SCHEMBL3718602 | 0.83 | RBP4 (0.72) | RBP4MEN1KMT2APOLBMAPT | |
| SCHEMBL27873728 | 0.82 | RBP4 (0.67) | RBP4MEN1KMT2ATRPV1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459209-A | Derivatives of N-acyl-N' -phenylpiperazines for the prevention or treatment of diabetes (etc.) | TAKEDA PHARMACEUTICAL | 2012-05-16 | — | — | CN | disclosed |
| WO-2010119992-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |