Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158329 | 1.00 | TLR9 (0.67) | TLR9ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL2787588 | 0.85 | TLR9 (0.80) | TLR9ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL1344341 | 0.85 | TLR9 (0.80) | TLR9ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL1344338 | 0.85 | TLR9 (0.80) | TLR9ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL10825832 | 0.80 | TLR9 (1.00) | TLR9ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL11431870 | 0.80 | TLR9 (0.58) | TLR9ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL10826201 | 0.80 | TLR9 (1.00) | TLR9ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL27560167 | 0.77 | LMNA (0.48) | TLR9ALDH1A1HSD17B10TDP1CYP1A2 | |
| SCHEMBL9484085 | 0.77 | TSHR (0.50) | TLR9ALDH1A1TDP1CYP2C9HTR6 | |
| SCHEMBL1035737 | 0.76 | TLR9 (0.67) | TLR9ALDH1A1HSD17B10TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102105485-B | Selectivity caspase inhibitors and uses thereof | NEW WORLD LABORATORIES INC. (CA) | 2016-01-13 | — | — | CN | disclosed |
| CN-102105485-A | Selective caspase inhibitors and uses thereof | NEW WORLD LAB INC | 2011-06-22 | — | — | CN | disclosed |
| WO-2010133000-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES INC. (CA) | 2010-11-25 | — | — | WO | disclosed |
| EP-0026519-B1 | PHOTOGRAPHIC SILVER HALIDE EMULSION MATERIAL CONTAINING AN ANTIFOGGANT PRECURSOR | AGFA-GEVAERT N.V. (BE) | 1983-08-17 | — | — | EP | disclosed |
| US-4307175-A | Photographic silver halide emulsion material containing an antifoggant precursor | AGFA-GEVAERT, N.V. (BE) | 1981-12-22 | — | — | US | disclosed |
| EP-0026519-A1 | Photographic silver halide emulsion material containing an antifoggant precursor | AGFA-GEVAERT N.V. (BE) | 1981-04-08 | — | — | EP | disclosed |
| US-4103089-A | ANTIHISTAMINES | MERRELL TORAUDE ET COMPAGNIE (FR) | 1978-07-25 | — | — | US | disclosed |