SCHEMBL1344341

SCHEMBL1344341

O=S(=O)(C=CS(=O)(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 2/20 0.80
HTR6 P50406 1/20 0.55
ALDH1A1 P00352 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
MCOLN3 Q8TDD5 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
PLA2G7 Q13093 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2787588 1.00 TLR9 (0.80) TLR9HTR6ALDH1A1CYP1A2CYP2C9
SCHEMBL1344338 1.00 TLR9 (0.80) TLR9HTR6ALDH1A1CYP1A2CYP2C9
SCHEMBL10825832 0.89 TLR9 (1.00) TLR9HTR6ALDH1A1CYP1A2CYP2C9
SCHEMBL10826201 0.89 TLR9 (1.00) TLR9HTR6ALDH1A1CYP1A2CYP2C9
SCHEMBL3718697 0.85 TLR9 (0.67) TLR9HTR6ALDH1A1CYP1A2CYP2C9
SCHEMBL777364 0.85 TLR9 (0.67) TLR9HTR6ALDH1A1CYP1A2CYP2C9
SCHEMBL11158329 0.85 TLR9 (0.67) TLR9HTR6ALDH1A1CYP1A2CYP2C9
SCHEMBL1035737 0.85 TLR9 (0.67) TLR9HTR6ALDH1A1CYP1A2CYP2C9
SCHEMBL10950780 0.85 TLR9 (0.67) TLR9HTR6ALDH1A1CYP1A2CYP2C9
SCHEMBL777365 0.85 TLR9 (0.67) TLR9HTR6ALDH1A1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122051385-A Additive for improving safety performance of electrolyte, electrolyte and battery 孝感楚能新能源创新科技有限公司 2026-05-15 CN claimed
CN-119638541-A Addition product of alkyl free radical and capture reagent, addition method and application thereof 深圳湾实验室坪山生物医药研发转化中心 2025-03-18 CN claimed
CN-116444330-A Addition product of alkyl free radical and capture reagent, addition method and application thereof 深圳湾实验室坪山生物医药研发转化中心 2023-07-18 CN claimed
US-6797745-B1 Hot melt inks containing styrene or terpene polymers XEROX CORPORATION 2004-09-28 US claimed
CN-122051385-A Additive for improving safety performance of electrolyte, electrolyte and battery 孝感楚能新能源创新科技有限公司 2026-05-15 CN disclosed
CN-122051385-A Additive for improving safety performance of electrolyte, electrolyte and battery 孝感楚能新能源创新科技有限公司 2026-05-15 CN disclosed
WO-2025090901-A1 ROS-ACTIVATED CO PRODRUGS FOR CANCER TREATMENT GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2025-05-01 WO disclosed
CN-119638541-A Addition product of alkyl free radical and capture reagent, addition method and application thereof 深圳湾实验室坪山生物医药研发转化中心 2025-03-18 CN disclosed
CN-116444330-A Addition product of alkyl free radical and capture reagent, addition method and application thereof 深圳湾实验室坪山生物医药研发转化中心 2023-07-18 CN disclosed
US-11279686-B2 Nrf2 activating compounds and uses thereof RIGEL PHARMACEUTICALS, INC. (US) 2022-03-22 US disclosed
US-20210078969-A1 Nrf2 Activating Compounds and Uses Thereof MIDCAP FINANCIAL TRUST 2021-03-18 US disclosed
EP-3411361-B1 NRF2 ACTIVATING COMPOUNDS AND USES THEREOF RIGEL PHARMACEUTICALS INC (US) 2020-11-25 EP disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed
EP-0127086-B1 PROCESS FOR THE PURIFICATION OF VITAMIN D3 AND OF VITAMIN D2 BASF Aktiengesellschaft (DE) 1986-10-29 EP disclosed
US-4529546-A Purification of vitamin D3 BASF AKTIENGESELLSCHAFT (DE) 1985-07-16 US disclosed
EP-0127086-A2 Process for the purification of vitamin D3 and of vitamin D2 BASF Aktiengesellschaft (DE) 1984-12-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210078969-A1 Nrf2 Activating Compounds and Uses Thereof NFE2L2, KEAP1, NQO1 TLR9 819/4885HTR6 3674/4885ALDH1A1 1408/4885
US-11279686-B2 Nrf2 activating compounds and uses thereof NFE2L2, KEAP1, NQO1 TLR9 819/4885HTR6 3674/4885ALDH1A1 1408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.