Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309576 | 0.86 | TYR (0.41) | MEN1KMT2ACYP3A4MAPTPPARG | |
| SCHEMBL3955351 | 0.79 | MEN1 (0.51) | MEN1KMT2ACYP3A4MAPTPPARG | |
| SCHEMBL2174877 | 0.74 | TYR (0.46) | MEN1KMT2AMAPTTYRTRIM24 | |
| SCHEMBL28162837 | 0.73 | TYR (0.54) | MEN1KMT2ACYP3A4MAPTTYR | |
| SCHEMBL14157089 | 0.73 | TDP1 (0.38) | MEN1KMT2ACYP3A4MAPTALDH1A1 | |
| SCHEMBL14156981 | 0.73 | ALDH1A1 (0.38) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL5760032 | 0.72 | TYR (0.53) | MEN1KMT2ACYP3A4MAPTPPARG | |
| SCHEMBL21830499 | 0.72 | TYR (0.65) | MEN1KMT2ACYP3A4MAPTPPARG | |
| SCHEMBL29492443 | 0.72 | TYR (0.65) | MEN1KMT2ACYP3A4MAPTPPARG | |
| SCHEMBL4443109 | 0.72 | CYP3A4 (0.56) | MEN1KMT2ACYP3A4MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010134082-A1 | CHROMENONE DERIVATIVES FOR TREATMENT OF CANCER | PROTEOLOGICS LTD (IL) | 2010-11-25 | — | — | WO | disclosed |