Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174674 | 0.86 | NR1H4 (0.45) | TYRMEN1MAPTKMT2AGAA | |
| SCHEMBL3955351 | 0.83 | MEN1 (0.51) | TYRBCHEACHETRIM24TRIM33 | |
| SCHEMBL4731187 | 0.81 | TYR (0.49) | TYRBCHEACHETRIM24TRIM33 | |
| SCHEMBL22365701 | 0.80 | TYR (0.65) | TYRBCHEACHETRIM24TRIM33 | |
| SCHEMBL4661084 | 0.80 | TYR (0.65) | TYRBCHEACHETRIM24TRIM33 | |
| SCHEMBL28100182 | 0.78 | TYR (0.44) | TYRBCHEACHETRIM24TRIM33 | |
| SCHEMBL5490550 | 0.78 | ALDH1A1 (0.43) | TYRBCHEACHEALDH1A1MEN1 | |
| SCHEMBL4070600 | 0.78 | BCHE (0.52) | TYRBCHEACHETRIM24TRIM33 | |
| SCHEMBL5207565 | 0.77 | TYR (0.48) | TYRBCHEACHETRIM24TRIM33 | |
| SCHEMBL5202082 | 0.76 | TYR (0.47) | TYRBCHEACHETRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346844-A1 | SUBSTITUTED BENZFUROCHROMENES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF BONE RELATED DISORDERS | Council Of Scientific & Industrial Research (IN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010052734-A1 | SUBSTITUTED BENZFUROCHROMENES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF BONE RELATED DISORDERS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-05-14 | — | — | WO | disclosed |