Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 4/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035958 | 0.74 | KDM4E (0.39) | KDM4EHTR6ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL13114046 | 0.74 | KDM4E (0.39) | KDM4EHTR6ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL474103 | 0.71 | HPGDS (0.51) | KDM4EATMALDH1A1 | |
| SCHEMBL28459041 | 0.69 | HTR6 (0.43) | HTR6ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL1466309 | 0.69 | KDM4E (0.43) | KDM4EHTR6ALDH1A1L3MBTL1HTT | |
| SCHEMBL6601315 | 0.68 | HTR2A (0.40) | CA12CA1CA2ALDH1A1MEN1 | |
| SCHEMBL15742051 | 0.68 | ABCB1 (0.39) | KDM4EHTR6ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL858846 | 0.68 | — | — | |
| SCHEMBL19244945 | 0.68 | NPC1 (0.43) | KDM4ECA12ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL3532776 | 0.67 | NPC1 (0.48) | KDM4EALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |