Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.56 |
| ▸ | ACACA | Q13085 | 6/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13076447 | 0.93 | ACACB (0.56) | ACACBACACAALOX5RORCTAS1R3 | |
| SCHEMBL3798078 | 0.91 | ALOX5 (0.57) | ACACBACACAALOX5TAS1R3TAS1R1 | |
| SCHEMBL3727288 | 0.88 | ACACB (0.46) | ACACBACACAALOX5TAS1R3TAS1R1 | |
| SCHEMBL13077221 | 0.88 | ACACB (0.57) | ACACBACACA | |
| SCHEMBL3726184 | 0.87 | ACACB (0.66) | ACACBACACAALOX5 | |
| SCHEMBL3722350 | 0.87 | TAS1R3 (0.56) | ACACBACACAALOX5TAS1R3TAS1R1 | |
| SCHEMBL3721454 | 0.87 | ACACB (0.47) | ACACBACACAALOX5TAS1R3TAS1R1 | |
| SCHEMBL3724748 | 0.87 | ACACB (0.47) | ACACBACACAALOX5 | |
| SCHEMBL3716764 | 0.87 | ACACB (0.54) | ACACBACACA | |
| SCHEMBL3726987 | 0.86 | ACACB (0.48) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |