Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 10/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PARG | Q86W56 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726989 | 0.87 | MTNR1A (0.50) | ACACBSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL3727291 | 0.87 | KDM4E (0.50) | ACACBSMN1; SMN2MTNR1AMTNR1BKDM4E | |
| SCHEMBL3720004 | 0.86 | ACACB (0.64) | ACACBSMN1; SMN2MTNR1AMTNR1BCES2 | |
| SCHEMBL3717478 | 0.86 | ACACB (0.64) | ACACBSMN1; SMN2MTNR1AMTNR1BCES2 | |
| SCHEMBL3722351 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2MTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL3724749 | 0.85 | ACACB (0.45) | ACACBSMN1; SMN2MTNR1AMTNR1BKDM4E | |
| SCHEMBL3720513 | 0.84 | MTNR1A (0.49) | ACACBSMN1; SMN2MTNR1AMTNR1BCES2 | |
| SCHEMBL3720624 | 0.84 | ALDH1A1 (0.49) | ACACBSMN1; SMN2MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL3718635 | 0.83 | PPARA (0.45) | ACACBSMN1; SMN2MTNR1AMTNR1BKDM4E | |
| SCHEMBL3727221 | 0.83 | ACACB (0.45) | ACACBSMN1; SMN2MTNR1AMTNR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |