Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | ACACB | O00763 | 7/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722807 | 0.94 | MTNR1A (0.49) | MTNR1AMTNR1BACACBSCN9AALDH1A1 | |
| SCHEMBL3723076 | 0.93 | MTNR1A (0.50) | MTNR1AMTNR1BACACBSCN9AMAPT | |
| SCHEMBL3721082 | 0.89 | MTNR1A (0.53) | MTNR1AMTNR1BACACBSCN9AMAPT | |
| SCHEMBL3720513 | 0.88 | MTNR1A (0.49) | MTNR1AMTNR1BACACBSCN9ARORC | |
| SCHEMBL3806067 | 0.86 | MTNR1A (0.44) | MTNR1AMTNR1BACACBSCN9A | |
| SCHEMBL3726989 | 0.85 | MTNR1A (0.50) | MTNR1AMTNR1BACACBSCN9ASMN1; SMN2 | |
| SCHEMBL3720064 | 0.84 | ACACB (0.50) | MTNR1AMTNR1BACACB | |
| SCHEMBL3723730 | 0.83 | SMN1; SMN2 (0.52) | ACACBSCN9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3722996 | 0.83 | MTNR1A (0.53) | MTNR1AMTNR1BACACBSCN9AMAPT | |
| SCHEMBL3722610 | 0.83 | ACACB (0.51) | MTNR1AMTNR1BACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |