Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 16/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726989 | 0.90 | MTNR1A (0.50) | ACACBMTNR1AMTNR1BACACA | |
| SCHEMBL3723076 | 0.90 | MTNR1A (0.50) | ACACBMTNR1AMTNR1B | |
| SCHEMBL3726202 | 0.88 | ACACB (0.58) | ACACBMTNR1AMTNR1B | |
| SCHEMBL3722610 | 0.86 | ACACB (0.51) | ACACBMTNR1AMTNR1BCYP3A4CYP2C9 | |
| SCHEMBL3720513 | 0.85 | MTNR1A (0.49) | ACACBMTNR1AMTNR1BACACA | |
| SCHEMBL3719787 | 0.84 | MTNR1A (0.50) | ACACBMTNR1AMTNR1B | |
| SCHEMBL3725388 | 0.84 | GLA (0.44) | ACACBCYP3A4 | |
| SCHEMBL3722807 | 0.84 | MTNR1A (0.49) | ACACBMTNR1AMTNR1B | |
| SCHEMBL3724124 | 0.84 | MTNR1A (0.49) | ACACBMTNR1AMTNR1B | |
| SCHEMBL3721012 | 0.82 | PDE4B (0.45) | ACACBCYP3A4CYP2C9ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |