Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | IDE | P14735 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HLCS | P50747 | 6/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 6/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715583 | 1.00 | TDP1 (0.58) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL28248497 | 0.89 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL8646561 | 0.88 | TDP1 (0.57) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL629531 | 0.86 | TDP1 (0.74) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL4740139 | 0.85 | TDP1 (0.60) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL2350071 | 0.85 | TDP1 (0.60) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL487045 | 0.85 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL1527196 | 0.84 | TDP1 (0.58) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL4454446 | 0.84 | TDP1 (0.58) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL3790437 | 0.84 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120171720-A1 | Method of Making Ribosomes | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-07-05 | — | — | US | disclosed |
| WO-2010117525-A1 | METHOD OF MAKING RIBOSOMES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-10-14 | — | — | WO | disclosed |
| WO-2007131286-A1 | NANOSTRUCTURES SUITABLE FOR DELIVERY OF AGENTS | APOLLO LIFE SCIENCES LIMITED (AU) | 2007-11-22 | — | — | WO | disclosed |
| WO-2002038796-A9 | METHODS FOR DETERMINING PROTEASE CLEAVAGE SITE MOTIFS | BETH ISRAEL HOSPITAL (US) | 2004-04-29 | — | — | WO | disclosed |
| WO-2002038796-A2 | METHODS FOR DETERMINING PROTEASE CLEAVAGE SITE MOTIFS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2002-05-16 | — | — | WO | disclosed |