SCHEMBL487045

SCHEMBL487045

O=C1N[C@H]2[C@H](CS[C@H]2CCCC(C(=O)O)C(=O)O)N1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.68
MEN1 O00255 1/20 0.68
ABL1 P00519 1/20 0.68
LMNA P02545 1/20 0.68
PKM P14618 1/20 0.68
IDE P14735 1/20 0.68
MAPK1 P28482 1/20 0.68
KMT2A Q03164 1/20 0.68
RIN1 Q13671 1/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
HLCS P50747 6/20 0.63
CA12 O43570 5/20 0.47
CA1 P00915 5/20 0.47
CA2 P00918 5/20 0.47
CA9 Q16790 5/20 0.47
FOLH1 Q04609 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6838821 0.92 TDP1 (0.62) TDP1MEN1ABL1LMNAPKM
SCHEMBL8958855 0.92 TDP1 (0.62) TDP1MEN1ABL1LMNAPKM
Iodide SCHEMBL2533594 0.91 TDP1 (0.61) TDP1MEN1ABL1LMNAPKM
SCHEMBL425273 0.90 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM
SCHEMBL5498960 0.90 TDP1 (0.60) TDP1MEN1ABL1LMNAPKM
SCHEMBL4464825 0.90 TDP1 (0.60) TDP1MEN1ABL1LMNAPKM
SCHEMBL8508662 0.90 TDP1 (0.60) TDP1MEN1ABL1LMNAPKM
SCHEMBL29375721 0.90 TDP1 (0.70) TDP1MEN1ABL1LMNAPKM
SCHEMBL2182339 0.90 TDP1 (0.60) TDP1MEN1ABL1LMNAPKM
SCHEMBL1936659 0.89 TDP1 (0.65) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 410 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US claimed
WO-2026107515-A1 INCRETIN HORMONE COMPOSITIONS AND METHODS USING SAME DIASOME PHARMACEUTICALS, INC. (US) 2026-05-21 WO claimed
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL DIASOME PHARMACEUTICALS INC (US) 2026-05-07 US claimed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US claimed
US-20240139288-A1 LIPID-BASED NANOPARTICLES AND USE OF SAME IN OPTIMIZED INSULIN DOSING REGIMENS SDG INC (US) 2024-05-02 US claimed
US-20240108585-A1 COMPOSITIONS COMPRISING LIPID-BASED NANOPARTICLES FOR TREATING DIABETES MELLITUS SDG, INC. 2024-04-04 US claimed
EP-2552202-B1 METHODS AND COMPOSITIONS FOR WEIGHT LOSS SDG INC (US) 2023-07-26 EP claimed
US-20230172868-A1 LIPID-BASED NANOPARTICLES WITH ENHANCED STABILITY SDG, INC. (US) 2023-06-08 US claimed
US-11517529-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2022-12-06 US claimed
EP-3952904-A1 LIPID-BASED NANOPARTICLES AND USE OF SAME IN OPTIMIZED INSULIN DOSING REGIMENS SDG, Inc. (US) 2022-02-16 EP claimed
CN-101237854-A Lipid construct for delivery of insulin to a mammal SDG INC (US) 2008-08-06 CN claimed
EP-1883394-A2 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, Inc. (US) 2008-02-06 EP claimed
EP-1883395-A2 LIPID CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL SDG, Inc. (US) 2008-02-06 EP claimed
WO-2006127361-A2 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. (US) 2006-11-30 WO claimed
WO-2006127360-A2 LIPID CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL SDG, INC. (US) 2006-11-30 WO claimed
US-20060228325-A1 Water soluble multi-biotin-containing compounds WILBUR D S 2006-10-12 US claimed
EP-1196199-A4 WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS UNIV WASHINGTON (US) 2002-06-19 EP claimed
EP-1196199-A2 WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS University of Washington (US) 2002-04-17 EP claimed
WO-2000072802-A2 WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS UNIVERSITY OF WASHINGTON (US) 2000-12-07 WO claimed
WO-1995025172-A1 RECOMBINANT ANTIBODY FRAGMENTS WHICH ARE SYNTHESIZED AND BIOTINYLATED IN E. COLI, THEIR USE IN IMMUNOASSAYS AND IMMUNOPURIFICATION TECHNIQUES UNIVERSITE LOUIS PASTEUR (FR) 1995-09-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108585-A1 COMPOSITIONS COMPRISING LIPID-BASED NANOPARTICLES FOR TREATING DIABETES MELLITUS IAPP, PNLIP, LIPC TDP1 4738/4885MEN1 1515/4885ABL1 2221/4885
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 TDP1 4819/4885MEN1 966/4885ABL1 4375/4885
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, SGMS2 TDP1 4755/4885MEN1 2415/4885ABL1 4626/4885
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL GPR119, INSR, FABP1 TDP1 4833/4885MEN1 2073/4885ABL1 4576/4885
US-20230172868-A1 LIPID-BASED NANOPARTICLES WITH ENHANCED STABILITY LIPA, NPC1L1, PLIN3 TDP1 3561/4885MEN1 1725/4885ABL1 2117/4885
US-11517529-B2 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 TDP1 4819/4885MEN1 966/4885ABL1 4375/4885
US-20060228325-A1 Water soluble multi-biotin-containing compounds BTD, HLCS, VNN1 TDP1 2706/4885MEN1 3462/4885ABL1 4752/4885
US-20240139288-A1 LIPID-BASED NANOPARTICLES AND USE OF SAME IN OPTIMIZED INSULIN DOSING REGIMENS PNLIP, IAPP, LIPC TDP1 4800/4885MEN1 561/4885ABL1 2416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.