Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718579 | 0.80 | PDE4B (0.49) | PDE4BSCN9ASCN7AKCNH2KDM2B | |
| SCHEMBL3719578 | 0.80 | PDE4B (0.53) | PDE4BSCN9ASCN7AKCNH2KDM2B | |
| SCHEMBL3717735 | 0.79 | PDE4B (0.57) | PDE4BSCN9ASCN7AKCNH2MAPT | |
| SCHEMBL3722547 | 0.78 | PDE4B (0.52) | PDE4BSCN9ASCN7AKCNH2KDM2B | |
| SCHEMBL3724294 | 0.77 | PDE4B (0.55) | PDE4BSCN9ASCN7AKCNH2TRPV1 | |
| SCHEMBL3721143 | 0.77 | PDE4B (0.51) | PDE4BSCN7AKCNH2KDM2BRAB9A | |
| SCHEMBL3718630 | 0.76 | PDE4B (0.54) | PDE4BSCN9ASCN7AKCNH2MAPT | |
| SCHEMBL17631295 | 0.75 | CYP2A6 (0.40) | KDM2BTRPV1MAPTHPGDRAB9A | |
| SCHEMBL3720131 | 0.75 | PDE4B (0.53) | PDE4BSCN9ASCN7AKCNH2TRPV1 | |
| SCHEMBL3717384 | 0.75 | PDE4B (0.53) | PDE4BSCN9ASCN7AKCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |