Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.45 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719578 | 0.95 | PDE4B (0.53) | PDE4BPARP10PARP15PARP2SCN7A | |
| SCHEMBL3721926 | 0.88 | PDE4B (0.44) | PDE4BPARP10PARP15PARP2ACACB | |
| SCHEMBL3726878 | 0.87 | PDE4B (0.48) | PDE4BPARP10PARP15SCN7AKCNH2 | |
| SCHEMBL3719600 | 0.87 | PDE4B (0.48) | PDE4BPARP10PARP15SCN7AKCNH2 | |
| SCHEMBL3721101 | 0.87 | PDE4B (0.44) | PDE4BPARP10PARP15PARP2ACACB | |
| SCHEMBL3724232 | 0.82 | PDE4B (0.46) | PDE4BPARP10PARP15PARP2ACACB | |
| SCHEMBL3725384 | 0.82 | PDE4B (0.50) | PDE4BACACBKDM2BACACA | |
| SCHEMBL3727011 | 0.82 | PDE4B (0.50) | PDE4BPARP10PARP15PARP2SCN7A | |
| SCHEMBL3720427 | 0.82 | ACACB (0.56) | PDE4BPARP10PARP15PARP2ACACB | |
| SCHEMBL3728782 | 0.81 | ACACA (0.56) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |