Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717384 | 0.85 | PDE4B (0.53) | PDE4BALDH1A1SCN7AKCNH2SCN9A | |
| SCHEMBL3721861 | 0.84 | PDE4B (0.53) | PDE4BALDH1A1RAB9AGRM1SCN7A | |
| SCHEMBL3717735 | 0.82 | PDE4B (0.57) | PDE4BALDH1A1RAB9ASCN7AKCNH2 | |
| SCHEMBL3724327 | 0.81 | MTNR1A (0.58) | ALDH1A1RAB9ASCN9ALMNAMAPT | |
| SCHEMBL3724294 | 0.80 | PDE4B (0.55) | PDE4BALDH1A1RAB9ASCN7AKCNH2 | |
| SCHEMBL3720134 | 0.80 | ALDH1A1 (0.48) | PDE4BALDH1A1RAB9ATHRBACACB | |
| SCHEMBL3719988 | 0.80 | PDE4B (0.53) | PDE4BALDH1A1RAB9ASCN7AKCNH2 | |
| SCHEMBL3721431 | 0.79 | PDE4B (0.53) | PDE4BALDH1A1SCN7AKCNH2SCN9A | |
| SCHEMBL3718630 | 0.79 | PDE4B (0.54) | PDE4BALDH1A1SCN7AKCNH2SCN9A | |
| SCHEMBL3724325 | 0.79 | ACACB (0.62) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |