Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.37 |
| ▸ | FAAH | O00519 | 6/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.35 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13191579 | 0.91 | BDKRB1 (0.44) | P2RX7BDKRB1SCD | |
| SCHEMBL3726047 | 0.83 | BDKRB1 (0.42) | BDKRB1 | |
| SCHEMBL13191215 | 0.82 | BDKRB1 (0.45) | BDKRB1SCD | |
| SCHEMBL13191406 | 0.81 | BDKRB1 (0.42) | P2RX7BDKRB1 | |
| SCHEMBL14856754 | 0.80 | TRPV1 (0.38) | TRPV1FAAHP2RX7BDKRB1 | |
| SCHEMBL13191263 | 0.79 | BDKRB1 (0.39) | P2RX7BDKRB1 | |
| SCHEMBL3723411 | 0.78 | BDKRB1 (0.44) | BDKRB1 | |
| SCHEMBL13191708 | 0.77 | BDKRB1 (0.48) | BDKRB1SCDNOTUM | |
| SCHEMBL14856605 | 0.77 | FAAH (0.35) | TRPV1FAAHBDKRB1 | |
| SCHEMBL3728256 | 0.76 | P2RY1 (0.37) | TRPV1FAAHNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |