Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719023 | 0.90 | FAAH (0.33) | P2RY1KDM4CFAAHTRPV1NOTUM | |
| SCHEMBL3723411 | 0.83 | BDKRB1 (0.44) | — | |
| SCHEMBL3722860 | 0.80 | GAA (0.33) | FAAHTRPV1 | |
| SCHEMBL3795493 | 0.79 | GAA (0.34) | FAAHTRPV1 | |
| SCHEMBL185223 | 0.79 | FAAH (0.35) | FAAHTRPV1SLC22A12ITGB1ITGA4 | |
| SCHEMBL185386 | 0.79 | LCK (0.37) | FAAHTRPV1 | |
| SCHEMBL3726047 | 0.78 | BDKRB1 (0.42) | — | |
| SCHEMBL186120 | 0.77 | JAK1 (0.34) | FAAHTRPV1CDK8 | |
| SCHEMBL3719959 | 0.76 | TRPV1 (0.37) | FAAHTRPV1NOTUM | |
| SCHEMBL14856612 | 0.76 | MAPK10 (0.33) | FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |