Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719592 | 0.86 | SLC5A2 (0.33) | CHRM5HCRTR1HCRTR2SCN7AKCNH2 | |
| SCHEMBL3719881 | 0.83 | MTNR1A (0.46) | RAF1 | |
| SCHEMBL3720075 | 0.83 | SCN9A (0.35) | PPARGSCN7AKCNH2SCN5ASCN2A | |
| SCHEMBL3717035 | 0.82 | SCN7A (0.46) | PPARGSCN7AKCNH2P2RX3SCN5A | |
| SCHEMBL3720434 | 0.82 | SCN7A (0.46) | PPARGSCN7AKCNH2P2RX3SCN5A | |
| SCHEMBL3720067 | 0.82 | PDE4B (0.46) | PPARGSCN7AKCNH2P2RX3SCN5A | |
| SCHEMBL3720757 | 0.81 | PPARG (0.38) | PPARG | |
| SCHEMBL3719589 | 0.81 | MAPT (0.34) | SCN7AKCNH2P2RX3SCN5ASCN2A | |
| SCHEMBL3724297 | 0.80 | ACACB (0.38) | PPARG | |
| SCHEMBL3724495 | 0.80 | PDE3B (0.34) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |